| 摘要 |
PROBLEM TO BE SOLVED: To provide a method for producing soyasapogenol B, by which the soyasapogenol B useful as a medicine or a raw material for medicines can newly be produced from sophoradiol (12-oleanene-3,22-diol). SOLUTION: This method for producing soyasapogenol B is characterized by the hydroxylation of the 24-position of the oleanane skeleton of sophoradiol with a hydroxylase originated from a plant culture product, such as the culture product of Glycyrrhiza glabra callus in a culture medium containing naphthalene acetic acid and 6-benzylaminopurine, while using the sophoradiol and NADPH as raw materials. COPYRIGHT: (C)2005,JPO&NCIPI
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