发明名称 |
Production of replicative hepatitis C virus |
摘要 |
A nucleic acid having a first nucleotide sequence encoding an infectious hepatitis C virus, a second nucleotide sequence encoding a ribozyme, and an inducible promoter operably linked to the first and second nucleotide sequences, the ribozyme being configured to remove a 3' sequence unnecessary for replication of the infectious hepatitis C virus from a transcript initiated by the inducible, is described. A cell containing the nucleic acid and methods of using the cell are also described.
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申请公布号 |
US2005118571(A1) |
申请公布日期 |
2005.06.02 |
申请号 |
US20040955447 |
申请日期 |
2004.09.30 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
SCHMIDT EMMETT V.;CHUNG RAYMOND T. |
分类号 |
C07K14/18;C12N7/00;C12N15/113;(IPC1-7):C12Q1/70;C12Q1/68;C07H21/04;C12N15/86 |
主分类号 |
C07K14/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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