发明名称 |
Stabilization and controlled delivery of ionic biopharmaceuticals |
摘要 |
Compositions and methods for stabilization and controlled release of ionic biopharmaceuticals are disclosed. Illustrative compositions according to the present invention include polyelectrolyte-PEG diblock copolymers complexed by ionic bonds with the ionic biopharmaceuticals. Additional illustrative compositions include microspheres encapsulating polyelectrolyte-PEG diblock copolymers complexed by ionic bonds with the ionic biopharmaceuticals. A method of delivering a biopharmaceutical to a person in need thereof involves administering microspheres that encapsulate biopharmaceutical/polyelectrolyte-PEG diblock copolymer complexes.
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申请公布号 |
US2005118718(A1) |
申请公布日期 |
2005.06.02 |
申请号 |
US20040948077 |
申请日期 |
2004.09.22 |
申请人 |
UNIVERSITY OF UTAH RESEARCH FOUNDATION |
发明人 |
BAE YOU H.;KIM JONG H.;TALUJA AJAY |
分类号 |
A61K47/48;A61K48/00;C07H21/04;(IPC1-7):C12N15/88;C07K14/47 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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