发明名称 |
CONTROLLED RELEASE HYDROCODONE FORMULATIONS |
摘要 |
A solid oral controlled-release oral dosage form of hydrocodone is disclosed. The dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and a sufficient amount of a controlled release material to render the dosage form suitable for twice-a-day administration to a human patient, the dosage form providing a C12/Cmax ratio of 0.55 to 0.85, said dosage form providing a therapeutic effect for at least about 12 hours. |
申请公布号 |
KR20050052544(A) |
申请公布日期 |
2005.06.02 |
申请号 |
KR20057007292 |
申请日期 |
2005.04.27 |
申请人 |
EURO-CELTIQUE S.A. |
发明人 |
OSHLACK BEN JAMIN;HUANG HUA PIN;TONELLI ALFRED P.;MASSELINK JOHN |
分类号 |
C07D489/02;A61K9/14;A61K9/16;A61K9/20;A61K9/22;A61K9/26;A61K9/48;A61K9/52;A61K31/485;A61P25/02;A61P25/04 |
主分类号 |
C07D489/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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