发明名称 |
3, 10, AND 12A SUBSTITUTED TETRACYCLINE COMPOUNDS |
摘要 |
The present invention pertains to novel 3, 10 and/or 12a-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression. Methods of preparing the novel 3, 10 and/or 12a-substituted tetracycline compounds are also disclosed. |
申请公布号 |
EP1534300(A2) |
申请公布日期 |
2005.06.01 |
申请号 |
EP20030764630 |
申请日期 |
2003.07.14 |
申请人 |
PARATEK PHARMACEUTICALS, INC. |
发明人 |
NELSON, MARK, L.;ISMAIL, MOHAMED, Y.;OHEMENG, KWASI;KIM, OAK;CHEN, JACKSON;BANDARAGE, UPUL |
分类号 |
A61K31/36;C07C237/26;A61K31/536;A61K31/65;A61P9/10;A61P11/00;A61P25/00;A61P25/16;A61P25/28;A61P27/02;A61P29/00;A61P35/00;A61P43/00;C07D265/12;C07D317/54 |
主分类号 |
A61K31/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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