Vaccine compositions comprising Omp85 proteins of Neisseria gonorrhoeae and Neisseria meningitidis

摘要

Nucleic acid and amino acid sequences of the Omp85 proteins of N. gonorrhoeae and N. meningitidis, and fragments thereof, as well as homologs and fusion products thereof, are useful in vaccine compositions for use in the protection of subjects against Neisserial disease such as non-symptomatic gonococcal infection or symptomatic disease and non-symptomatic meningococcal infection and symptomatic disease. Antibodies developed to these proteins and peptides are also useful in the vaccine compositions.