| 摘要 |
An objective of the present invention is to provide compounds which have inhibitory activity against autophosphorylation of macrophage colony-stimulating factor receptors. The compounds of the present invention are represented by formula (I) and salt and solvate thereof: <CHEM> wherein X represents CH or N; Z represents O or S; R<1>, R<2>, and R<3> represent H, optionally substituted alkoxy or the like; R<4> represents H; R<5>, R<6>, R<7>, and R<8> represent H, halogen, alkyl, alkoxy, trifluoromethyl or the like; R<9> and R<10> represent H, alkyl or the like; and any one of R<11> and R<12> represents H with the other representing alkyl and R<13> represents an optionally substituted carbocyclic or heterocyclic ring or the like, or R<11> represents H and R<12> and R<13> combine together to form a bicyclic carbocyclic ring.
|
