| 摘要 |
Benzene sulfonamide derivatives (I), their enantiomers, diastereoisomers and salts with acids or bases are new. <??>Benzene sulfonamide derivatives of formula (I), their enantiomers, diastereoisomers and salts with acids or bases are new. <??>G = -NR<1>R<2>; <??>R<1> and R<2> = H, alkyl, cycloalkyl, aryl (optionally substituted), arylalkyl (optionally substituted),cycloalkyl, cycloalkylalkyl, heteroaryl (optionally substituted), or heteroarylalkyl (optionally substituted), or together R<1>-N-R<2> forms a 5-7 membered heterocycloalkyl group containing which may contain O or a second N atom in the ring and may be substituted by alkyl, cycloalkyl, cycloalkylalkyl, aryl (optionally substituted), arylalkyl (optionally substituted), arylcarbonyl (optionally substituted), arylcarbonylalkyl (optionally substituted), diarylalkyl (optionally substituted), diarylalkenyl (optionally substituted), heteroaryl (optionally substituted), heteroarylalkyl (optionally substituted), heteroarylcarbonyl (optionally substituted), or heteroarylcarbonylalkyl (optionally substituted); <??>R<3> = H, alkyl or phenyl optionally substituted; <??>Ra = OH, alkoxy, aryloxy (optionally substituted), arylalkyloxy (optionally substituted), amino, alkylamino, dialkylamino, arylamino (optionally substituted), or arylalkylamino (optionally substituted); <??>Rb and Rc = H, halogen, alkyl, alkoxy, OH or trihaloalkyl; <??>m = 0 or 1; <??>n and q = 0-6; <??>p and r = 1-6. |
