| 发明名称 |
HETEROARYL SUCCINAMIDES AND THEIR APPLICATION AS INHIBITORS OF METALLOPROTEINASE |
| 摘要 |
The invention relates to a compound with the formula where the meanings of R1, R2, R3, R4, R5, X, Y, and Ia are listed in the description. The compounds are used for the inhibition of the activity of metalloproteinase by reaction between the metalloproteinase and an effective quantity of the compounds in accordance with the invention.
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| 申请公布号 |
BG64506(B1) |
申请公布日期 |
2005.05.31 |
| 申请号 |
BG19990103415 |
申请日期 |
1999.05.20 |
| 申请人 |
AGOURON PHARMACEUTICALS, INC.;SYNTEX (U.S.A.) INC. |
发明人 |
BENDER STEVEN;CASTELHANO ARLINDO;CHONG WESLEY;ABREO MELWYN;BILLEDEAU ROLAND;CHEN JIAN;DEAL JUDITH |
| 分类号 |
C07D233/58;A61K31/00;A61K31/34;A61K31/341;A61K31/38;A61K31/381;A61K31/40;A61K31/4025;A61K31/407;A61K31/415;A61K31/4164;A61K31/4178;A61K31/44;A61K31/4427;A61K31/443;A61K31/4433;A61K31/4436;A61K31/4439;A61K31/55;A61K38/00;A61P1/00;A61P1/02;A61P9/00;A61P9/10;A61P19/00;A61P19/02;A61P19/10;A61P29/00;A61P35/00;A61P43/00;C07D207/32;C07D207/327;C07D207/337;C07D231/12;C07D233/54;C07D233/56;C07D307/54;C07D333/24;C07D333/26;C07D401/04;C07D401/10;C07D401/12;C07D401/14;C07D403/12;C07D405/10;C07D405/12;C07D405/14;C07D409/12;C07D487/04;C07D487/08;C07D498/08;C07D521/00;C07K5/072;(IPC1-7):C07D207/327;C07D403/00;C07D405/00;A61K38/05;C07D401/00 |
主分类号 |
C07D233/58 |
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