发明名称 |
Method for producing aspartame derivative, method for purifying the same, crystals thereof and uses of the same |
摘要 |
N-[N-[3-(3-methoxy-4-hydroxyphenyl)propyl]-L-alpha-aspartyl]-L-phenylalanine 1-methyl ester is prepared by a process comprising: subjecting Aspartame and 3-(3-methoxy-4-hydroxyphenyl)propionaldehyde or derivatives thereof to reductive alkylation in a solvent to produce N-[N-[3-(3-methoxy-4-hydroxyphenyl)propyl]-L-alpha-aspartyl]-L-phenylalanine 1-methyl ester; and crystallizing said compound.
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申请公布号 |
US6899912(B2) |
申请公布日期 |
2005.05.31 |
申请号 |
US20020091500 |
申请日期 |
2002.03.07 |
申请人 |
AJINOMOTO CO., INC. |
发明人 |
AMINO YUSUKE;YUZAWA KAZUKO;TAKEMOTO TADASHI |
分类号 |
A23L1/236;C07K5/072;C07K5/075;(IPC1-7):A23L1/236;C07C229/00 |
主分类号 |
A23L1/236 |
代理机构 |
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地址 |
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