Inhalable formulation of a solution containing a tiotropium salt

摘要

Describes a propellant-free inhalable pharmaceutical preparation comprising a tiotropium salt as active substance, in a concentration based on tiotropium of between 0.0005 and 5 % by weight, water on its own or a water/ethanol mixture as solvent for the active substance, acid for achieving a pH between 2.0 and 3.1, a preservative, editic acid or a salt thereof in an amount of greater than 0 up to 25 mg/100 ml, optionally a cosolvent and/or other adjuvants and additives in addition to the preservative. Describes the use of the pharmaceutical preparation for nebulising in an inhaler, and as a medicament including for the treatment of asthma and/or COPD.