| 发明名称 |
Method of screening prion disease infection factor |
| 摘要 |
A screening method for infectious agents of human prion diseases in samples is described. The method comprises detecting the deposition of an aberrant prion protein in the follicular dendritic cell (FDC) of a knock-in non-human animal that expresses a humanized prion protein gene. Also described is a method of screening for preventive or therapeutic agents for human prion diseases.
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| 申请公布号 |
NZ527769(A) |
申请公布日期 |
2005.05.27 |
| 申请号 |
NZ20020527769 |
申请日期 |
2002.01.31 |
| 申请人 |
JAPAN AS REPRESENTED BY PRESIDENT OF TOHOKU UNIVERSITY |
发明人 |
KITAMOTO, TETSUYUKI;MIYOSHI, ICHIRO;MOHRI, SHIROU |
| 分类号 |
A01K67/027;C07K14/47;C12N5/10;C12N15/09;C12Q1/02;C12R1/91;G01N33/50;G01N33/569;G01N33/68;(IPC1-7):G01N33/15 |
主分类号 |
A01K67/027 |
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