发明名称 |
Specific cyclolignans for treating insulin-like growth factor-1 receptor dependent diseases |
摘要 |
Use of specific cyclolignans for treating insulin-like growth factor-1 receptor (IGF-1R) dependent diseases by inhibiting the insulin-like growth factor-1 receptor is disclosed, wherein the carbon atoms in positions 9 and 9' of these cyclolignans have cis configuration. Specific cyclolignans such as picropodophyllin can be used for the treatment of IGF-1R dependent diseases, such as cancer, psoriasis, artherosclerosis and acromegaly. |
申请公布号 |
NZ530290(A) |
申请公布日期 |
2005.05.27 |
申请号 |
NZ20020530290 |
申请日期 |
2002.06.19 |
申请人 |
BIOVITRUM AB |
发明人 |
LARSSON, OLLE;AXELSON, MAGNUS |
分类号 |
A61K31/34;A61K31/36;A61K31/365;A61P5/06;A61P9/10;A61P17/06;A61P35/00;A61P35/02;A61P43/00;C07D317/54;C07D317/70;C07D493/04 |
主分类号 |
A61K31/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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