摘要 |
<p>The invention features quaternary ammonium compounds of formula (I), and any stereoisomers thereof, wherein R1 is selected from C1-C6 alkyl, -CH2-(C1-C4 alkenyl), and -CH2-(C1-C6 alkynyl), each of which is optionally substituted with a group selected from phenyl, C1-C4 alkoxy, and hydroxyl; and X represents an anion of a pharmaceutically acceptable acid, and their use in treating asthma, chronic obstructive pulmonary disorder, allergic rhinitis, and infectious rhinitis.</p> |