发明名称 |
Method of immobilizing a substance of interest to a solid phase |
摘要 |
Methods are described for attaching molecules to a solid phase, such as a magnetic bead. Free amine groups on the solid surface react with a molecule that contains a sulfhydryl group. The sulfhydryl group may, but need not be protected. The molecule is then reacted with a conjugate of linker and ligand. The liner has a reactive maleimide or sulfhydryl group which reacts with the molecule on the solid phase.
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申请公布号 |
US2005112786(A1) |
申请公布日期 |
2005.05.26 |
申请号 |
US20030723923 |
申请日期 |
2003.11.25 |
申请人 |
WANG QING;LEVINE DANIEL M.;PARKER THOMAS S. |
发明人 |
WANG QING;LEVINE DANIEL M.;PARKER THOMAS S. |
分类号 |
G01N33/543;(IPC1-7):G01N33/553 |
主分类号 |
G01N33/543 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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