发明名称 |
GENES DIFFERENTIALLY EXPRESSED BY ACUTELY ISOLATED RESIDENT PROGENITOR CELLS OF THE HUMAN WHITE MATTER |
摘要 |
<p>The present invention relates to a method of modulating production of neuron s and/or oligodendrocytes from neural progenitor cells of human white matter a nd to a method of treating a subject for a condition modulated by underproducti on of oligodendrocytes from human white matter. Both of these methods involve administering an agonist or antagonist of one or more molecules set forth in Tables 1 and/or 2 to the neural progenitor cells. Also disclosed is a method of using an inhibitor of sterol synthesis to differentiate oligodendrocyte progenitor cells to oligodendrocytes.</p> |
申请公布号 |
CA2547474(A1) |
申请公布日期 |
2005.05.26 |
申请号 |
CA20042547474 |
申请日期 |
2004.11.10 |
申请人 |
CORNELL RESEARCH FOUNDATION, INC. |
发明人 |
GOLDMAN, STEVEN A.;FRASER, SIM |
分类号 |
A61K38/51;A61K;A61K31/00;A61K31/737;A61K38/00;A61K38/17;A61K38/18;A61K38/43;A61K38/46;A61P21/00;A61P25/00;C12N1/38;C12N5/08;G01N33/68 |
主分类号 |
A61K38/51 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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