| 摘要 |
The present invention is directed to recombinant alphavirus vectors and expression of heterologous antigens therefrom in animal cells. Said vectors are characterized by having inter alia an alphavirus 3'-untranslated region (3'-UTR) comprising a deletion of non-essential nucleotides, suitably a deletion of at least 525 nucleotides. Recombinant alphavirus vectors of the present invention can be used for preparing antigenic compositions which can be administered as vaccines. |
