发明名称 |
INJECTION SOLUTION COMPRISING AN LHRH ANTAGONIST |
摘要 |
The aqueous injection solution comprising an LHRH antagonist contains in addition to the LHRH antagonist, such as cetrorelix, an organic, physiologically compatible acid and optionally a surfactant and also a framework builder. The LHRH antagonist has significantly improved solubility and can be prepared in higher concentrations and with an improved bioavailability. The aggregation tendency of the LHRH antagonist is significantly reduced. |
申请公布号 |
ZA200404051(B) |
申请公布日期 |
2005.05.25 |
申请号 |
ZA20040004051 |
申请日期 |
2004.05.25 |
申请人 |
ZENTARIS GMBH;ZENTARIS IVF GMBH |
发明人 |
Jurgen ENGEL;Horst BAUER;Werner SARLIKIOTIS;Matthias RISCHER;Frank GUTHLEIN;Dominique DI STEFANO |
分类号 |
A61K9/08;A61K9/00;A61K38/04;A61K38/09;A61K47/10;A61K47/12;A61K47/22;A61K47/26;A61P5/12;A61P5/36;A61P43/00 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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