发明名称 |
Method for high-throughput screening with a calorimetric device |
摘要 |
A method is disclosed for high-throughput screening assay sample preparation and testing for the identification of binding between drug targets and library compounds, for use with a calorimetric device measuring the enthalpy of reaction for the binding. The method includes mixing a library compound with a specified solvent and mixing a target compound solution with a second specified solvent on a calorimetric device. The library compound/solvent is merged with the target compound/solvent solution and the library compound/solvent solution is also merged with a third solvent solution on the calorimetric device. The heats of reaction are detected for both merged solutions and are compared. |
申请公布号 |
EP1533608(A2) |
申请公布日期 |
2005.05.25 |
申请号 |
EP20040025543 |
申请日期 |
2004.10.27 |
申请人 |
PALO ALTO RESEARCH CENTER INCORPORATED |
发明人 |
BRUCE, RICHARD H.;TORRES, FRANCISCO E.;BELL, ALAN G.;PEETERS, ERIC |
分类号 |
G01N25/48;B01J19/00;C40B50/08;G01N37/00;(IPC1-7):G01N25/48 |
主分类号 |
G01N25/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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