| 发明名称 |
Pyrrolopyrimidines and related analogs as HSP90-inhibitors |
| 摘要 |
Pyrrolopyrimidines and related analogs are described and demonstrated to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents used in the treatment and prevention of various HSP90 mediated disorders, e.g., proliferative disorders. Methods of synthesis and use of such compounds are also described and claimed.
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| 申请公布号 |
US2005107343(A1) |
申请公布日期 |
2005.05.19 |
| 申请号 |
US20040945851 |
申请日期 |
2004.09.20 |
| 申请人 |
CONFORMA THERAPEUTICS CORPORATION |
发明人 |
KASIBHATLA SRINIVAS R.;SHI JIANDONG;LE BRAZIDEC JEAN-YVES;BIAMONTE MARCO A.;HONG KEVIN D.;BOEHM MARCUS F. |
| 分类号 |
A61K31/519;A61K31/5377;A61K31/541;A61K31/675;C07D;C07D473/12;C07D487/02;C07F9/02;C07F9/6515;(IPC1-7):A61K31/675;C07F9/651 |
主分类号 |
A61K31/519 |
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