COMPOSITIONS CONTAINING PHOSPHATIDIC ACID, METHODS OF USE THEREOF, METHODS OF MANUFACTURE THEREOF, AND ARTICLES OF MANUFACTURE CONTAINING SAME

摘要

Phosphatidic acid compositions, uses thereof and methods of manufacture thereof. Compositions include a physiologically effective amount of phosphatidic acid and carriers and excipients. Physiologic effectiveness is with regard to at least one of: amelioration of insulin resistance; improvement of glucose metabolism; reduction of cortisol level; treatment of depression; relief of stress associated symptoms; and improvement of mood. Preferably, phosphatidic acid is produced from lecithin by reaction with phospholipase-D. Compositions further including phosphatidylserine are also disclosed.