发明名称 |
COMBINATION THERAPY WITH GLATIRAMER ACETATE AND SIMVASTATIN FOR THE TREATMENT OF MULTIPLE SCLEROSIS |
摘要 |
The subject invention provides a method of treating a subject afflicted with a form of multiple sclerosis comprising periodically administering to the subject an amount of glatiramer acetate and an amount of simvastatin, wherein the amounts when taken together are effective to alleviate a symptom of the form of multiple sclerosis in the subject so as to thereby treat the subject. The subject invention also provides a package comprising glatiramer acetate, simvastatin and instructions for use of the together to alleviate a symptom of a form of multiple sclerosis in a subject. Additionally, the subject invention provides a pharmaceutical composition comprising an amount of glatiramer acetate and an amount of simvastatin, wherein the amounts when taken together are effective to alleviate a symptom of a form of multiple sclerosis in a subject. The subject invention further provides a pharmaceutical combination comprising separate dosage forms of an amount of glatiramer acetate and an amount of simvastatin, which combination is useful to alleviate a symptom of a form of multiple sclerosis in a subject.
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申请公布号 |
WO2004078145(B1) |
申请公布日期 |
2005.05.19 |
申请号 |
WO2004US06806 |
申请日期 |
2004.03.04 |
申请人 |
TEVA PHARMACEUTICAL INDUSTRIES, LTD.;TEVA PHARMACEUTICALS USA, INC.;HAYARDENY, LIAT;KOFLER, DINA |
发明人 |
HAYARDENY, LIAT;KOFLER, DINA |
分类号 |
A61K;A61K31/35;A61K38/00;A61P43/00;(IPC1-7):A61K31/35 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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