发明名称 COMBINATION THERAPY WITH GLATIRAMER ACETATE AND SIMVASTATIN FOR THE TREATMENT OF MULTIPLE SCLEROSIS
摘要 The subject invention provides a method of treating a subject afflicted with a form of multiple sclerosis comprising periodically administering to the subject an amount of glatiramer acetate and an amount of simvastatin, wherein the amounts when taken together are effective to alleviate a symptom of the form of multiple sclerosis in the subject so as to thereby treat the subject. The subject invention also provides a package comprising glatiramer acetate, simvastatin and instructions for use of the together to alleviate a symptom of a form of multiple sclerosis in a subject. Additionally, the subject invention provides a pharmaceutical composition comprising an amount of glatiramer acetate and an amount of simvastatin, wherein the amounts when taken together are effective to alleviate a symptom of a form of multiple sclerosis in a subject. The subject invention further provides a pharmaceutical combination comprising separate dosage forms of an amount of glatiramer acetate and an amount of simvastatin, which combination is useful to alleviate a symptom of a form of multiple sclerosis in a subject.
申请公布号 WO2004078145(B1) 申请公布日期 2005.05.19
申请号 WO2004US06806 申请日期 2004.03.04
申请人 TEVA PHARMACEUTICAL INDUSTRIES, LTD.;TEVA PHARMACEUTICALS USA, INC.;HAYARDENY, LIAT;KOFLER, DINA 发明人 HAYARDENY, LIAT;KOFLER, DINA
分类号 A61K;A61K31/35;A61K38/00;A61P43/00;(IPC1-7):A61K31/35 主分类号 A61K
代理机构 代理人
主权项
地址