发明名称 |
Metabolically engineered bacterial strains having enhanced 2-keto-D-gluconate accumulation |
摘要 |
The present invention relates to a method of altering bacterial host cells to accumulate 2-keto-D-gluconic acid (2-KDG) by inactivating an endogenous membrane bound 2-keto-D-gluconate dehydrogenase (2-KDGDH), which prior to inactivation catalyzed the conversion of 2-KDG to 2,5-diketogluconate (2,5-DKG).
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申请公布号 |
US2005106693(A1) |
申请公布日期 |
2005.05.19 |
申请号 |
US20040899602 |
申请日期 |
2004.07.27 |
申请人 |
DODGE TIMOTHY C.;RASHID M. H.;VALLE FERNANDO |
发明人 |
DODGE TIMOTHY C.;RASHID M. H.;VALLE FERNANDO |
分类号 |
C12N;C12N1/21;C12N9/04;C12N15/74;C12P7/58;C12P7/60;C12P19/02;(IPC1-7):C12P7/58 |
主分类号 |
C12N |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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