发明名称 Process for the removal of porogens from temperature sensitive macroreticular polymers using steam at reduced pressure
摘要 The present invention relates to an improved method of making a resin including steam stripping porogen from a polymer under vacuum. Optionally, the method includes diluting to remove process aids, and low pressure steam stripping to effect porogen removal. The invention makes adsorbent resins, and adsorbent resins free of animal derived products. In another aspect, the invention provides for a resin made using the improved method, and a downstream product made utilizing the resin in a manufacturing process used to make the product. The downstream product is a drug or precursor thereof, and is optionally cephalosporin C and insulin.
申请公布号 US2005107581(A1) 申请公布日期 2005.05.19
申请号 US20030715257 申请日期 2003.11.17
申请人 ROSENBAUM BRUCE 发明人 ROSENBAUM BRUCE
分类号 C07D501/28;A61K9/16;A61K31/545;A61K38/28;A61K47/30;B01D3/10;B01D3/38;B01J20/26;B01J20/30;C07D501/00;C07K14/62;C08F6/06;C08F6/16;C08G2/00;C08J3/12;C08J5/00;C08J9/28;(IPC1-7):C08G2/00 主分类号 C07D501/28
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