发明名称 |
REMOVAL OF HIGH MOLECULAR WEIGHT AGGREGATES USING HYDROXYAPATITE CHROMATOGRAPHY |
摘要 |
This invention relates to the application of hydroxyapatite chromatography to the purification of at least one antibody from a preparation containing high molecular weight aggregates. Further, this invention relates to an integration of ceramic hydroxyapatite chromatography into a combination chromatographic protocol for the removal of high molecular weight aggregates from an antibody preparation. |
申请公布号 |
CA2543193(A1) |
申请公布日期 |
2005.05.19 |
申请号 |
CA20042543193 |
申请日期 |
2004.10.06 |
申请人 |
WYETH |
发明人 |
KELLEY, BRIAN;GALLO, CHRISTOPHER;SUN, SHUJUN |
分类号 |
C07K16/06;B01D15/08;B01D15/26;B01D15/36;B01D15/38;B01J20/282;C07K16/22 |
主分类号 |
C07K16/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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