| 摘要 |
Polyoxyethlene sorbitan monooleate ("PSM" or "polysorbate 80") can be used in dietary supplements as a prebiotic for the stimulation of probiotic bacteria growth, even when present in only milligram quantities, e.g., 5-100 mg/dose. However, being a viscous liquid, PSM must be dried before incorporation. Moreover, it has been demonstrated that water activity in a probiotic formulation will greatly reduce the shelf-life of the formulation. Thus, even once the PSM is dried, extended shelf-life can be gained by reducing the water activity of the entire formulation. Disclosed herein is the use of dry PSM in formulations to enhance growth of probiotics, and reducing the formulation water activity to avoid reducing shelf-life.
|
