发明名称 RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA)
摘要 This invention relates to compounds, compositions, and methods useful for modulating gene expression using short interfering nucleic acid (siNA) molecules. In particular, the instant invention features small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules and methods used to modulate the expression of genes, such as expressed pseudogenes associated with the maintenance or development of diseases, disorders, traits, and conditions in a subject or organism.
申请公布号 WO2005044981(A2) 申请公布日期 2005.05.19
申请号 WO2004US27403 申请日期 2004.08.20
申请人 SIRNA THERAPEUTICS, INC.;HAEBERLI, PETER;MCSWIGGEN, JAMES 发明人 HAEBERLI, PETER;MCSWIGGEN, JAMES
分类号 A61K38/00;C12N5/02;C12N5/22;C12N15/11;C12N15/113;C12N15/87 主分类号 A61K38/00
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