摘要 |
The present invention relates to (+)-trans-isomers of (1-phosphonomethoxy-2- alkylcyclopropyl)methyl nucleoside derivatives of the formula (1) which are useful as an antiviral agent (particularly, against hepatitis B virus), pharmaceutically acceptable saltss, hydrates, or solvates thereof, and processes for the preparation of stereoisomers of the compounds of the formula (1), and a composition for the treatment of viral diseases (particularly, against hepatitis B virus) comprising (+)-trans-isomer of the compound of the formula (1), pharmaceutically acceptable salt, hydrate, or solvate thereof as an active substance.
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申请人 |
LG LIFE SCIENCES LTD.;CHOI, JONG-RYOO;HWANG, JAE-TAEG;CHO, DONG-GYU;ROH, KEE-YOON;KIM, CHUN-HYUNG;KIM, CHUNG-MI;HAN, MIN-JOON;KIM, JEONG-MIN;CHO, WOO-YOUNG;KIM, GYOUNG-WON;AHN, SINBYOUNG |
发明人 |
CHOI, JONG-RYOO;HWANG, JAE-TAEG;CHO, DONG-GYU;ROH, KEE-YOON;KIM, CHUN-HYUNG;KIM, CHUNG-MI;HAN, MIN-JOON;KIM, JEONG-MIN;CHO, WOO-YOUNG;KIM, GYOUNG-WON;AHN, SINBYOUNG |