发明名称 |
Compositions for TRP-M8 binding and radioreceptor methods therewith |
摘要 |
One embodiment of the invention is a composition that comprises a radioactive <SUP>32</SUP>P or <SUP>33</SUP>P phosphine oxide molecule. The said composition is designed to bind to the transient potential receptor-M8 (TRP-M8) receptor of cells. The radioactive <SUP>32</SUP>P or <SUP>33</SUP>P phosphine oxide ligand may be used for radioreceptor binding studies and for diagnostic studies of cancerous tissues. The TRP-M8 receptor is selectively expressed in malignant tissues such as prostate cancer cells. Affinity of the <SUP>32</SUP>P or <SUP>33</SUP>P phosphine oxide ligand for the TRP-M8 receptor confers selectively and specificity in delivering lethal radiation to the diseased cells.
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申请公布号 |
US6893626(B2) |
申请公布日期 |
2005.05.17 |
申请号 |
US20030370483 |
申请日期 |
2003.02.18 |
申请人 |
WEI EDWARD T. |
发明人 |
WEI EDWARD T. |
分类号 |
A61K51/02;C07F9/53;G01N33/60;(IPC1-7):A61K51/00 |
主分类号 |
A61K51/02 |
代理机构 |
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