Carbamoyl tetrahydropyridine derivatives

摘要

Carbamoyl tetrahydropyridine derivatives represented by the formula: [in the formula, R¹ and R² are identical or different, and each represents a hydrogen atom, a C₁-C₅ alkyl group, or the like; Y¹-Y² represents (R⁴)C-C(R⁵), (R⁶)C-N, N-N, (R⁷) N-CO, or N-C(R⁸); X¹, X², and X³ are identical or different, and each represents a hydrogen atom, a halogen atom, or the like; R³, R⁴, R⁵, and R⁶ are identical or different, and each represents a hydrogen atom or an alkyl group; R⁷ represents a hydrogen atom, a C₁-C₅ alkyl group, or the like; and R⁸ represents a hydrogen atom or a carbamoyl group] or a pharmaceutically acceptable salt thereof, and intermediates for the preparation thereof are provided. The derivatives described above are effective for diseases which are believed to involve CRF.