发明名称 |
N-containing cycloalkyl-substituted amino-thiazole derivatives and pharmaceutical compositions for inhibiting cell proliferation and methods for their use |
摘要 |
Aminothiazole compounds with N-containing cycloalkyl at the 2-amino position which are represented by the Formula (I), or a pharmaceutically acceptable prodrug of said compound, pharmaceutically active metabolite or pharmaceutically acceptable salt of said compound, or metabolite thereof, modulate and/or inhibit the cell proliferation and activity of protein kinases. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating malignancies and other disorders by administering effective amounts of such compounds.
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申请公布号 |
US2005101595(A1) |
申请公布日期 |
2005.05.12 |
申请号 |
US20040783887 |
申请日期 |
2004.02.20 |
申请人 |
PFIZER INC. |
发明人 |
CHU SHAO SONG;ALEGRIA LARRY A.;BLECKMAN TED M.;CHONG WESLEY K.M.;DUVADIE ROHIT KUMAR;LI LIN;ROMINES WILLIAM H.III;YANG YI |
分类号 |
A61K31/427;A61K31/454;A61K31/55;A61P35/00;C07D417/02;C07D417/12;C07D417/14;C07D471/04;C07D491/08;C07D513/04;(IPC1-7):A61K31/55 |
主分类号 |
A61K31/427 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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