摘要 |
Methods and compositions that can be used to make monatin or salt thereof from glucose, tryptophan, indole-3-lactic acid, indole-3-pyruvate, and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid, are provided. Methods are also disclosed for producing the indole-3-pyruvate and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid intermediates. Compositions provided include nucleic acid molecules, polypeptides, chemical structures, and cells. Methods include in vitro and in vivo processes, and the in vitro methods include chemical reactions. |
申请人 |
CARGILL, INC.;MCFARLAN, SARA C.;HICKS, PAULA M.;ZIDWICK, MARY JO;SANCHEZ-RIERA, FERNANDO A.;CAMERON, DOUGLAS C.;DESOUZA, MERVYN L.;ROSAZZA, JACK;GORT, STEVEN J. |
发明人 |
MCFARLAN, SARA C.;HICKS, PAULA M.;ZIDWICK, MARY JO;SANCHEZ-RIERA, FERNANDO A.;CAMERON, DOUGLAS C.;DESOUZA, MERVYN L.;ROSAZZA, JACK;GORT, STEVEN J. |