发明名称 |
Sustained-release preparation containing 5-acetyl-4,6-dimethyl-2[2-[4-(2-methoxyphenyl) piperazinyl]ethylamino]pyrimidine trihydrochloride as active ingredient |
摘要 |
A sustained-release formulation of 5-acetyl-4,6-dimethyl-2-[2-[4-(2-methoxyphenyl)piperazinyl]ethylamino]pyrimidine trihydrochloride coated with a release-controlling film comprising a water-insoluble polymer film having no hydrophilic group. The formulation of the present invention has such a release pattern that the drug release lasts for 20 hours or more, so that can be appropriately administered for treatment. Furthermore, the formulation itself is so stable that its release pattern does not change with pH and the formulation does not suffer from deterioration, coloration and the like with the lapse of time.
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申请公布号 |
US2005101606(A1) |
申请公布日期 |
2005.05.12 |
申请号 |
US20030399686 |
申请日期 |
2003.04.22 |
申请人 |
SEKIYA NOBORU;II YOSHINORI;ISHIKAWA MASAYUKI;AZUMA HIROSHI |
发明人 |
SEKIYA NOBORU;II YOSHINORI;ISHIKAWA MASAYUKI;AZUMA HIROSHI |
分类号 |
A61K9/16;A61K9/28;A61K9/50;A61K31/506;A61P13/00;(IPC1-7):A61K31/506;A61K9/22 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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