发明名称 |
PHAGE ANTIBODIES TO RADIATION-INDUCIBLE NEOANTIGENS |
摘要 |
<p>A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. The method includes the steps of: (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are therapeutic and diagnostic methods using targeting ligands that bind an irradiated tumor.</p> |
申请公布号 |
WO2005042780(A1) |
申请公布日期 |
2005.05.12 |
申请号 |
WO2004US34719 |
申请日期 |
2004.10.20 |
申请人 |
VANDERBILT UNIVERSITY;HALLAHAN, DENNIS, E.;MERNAUGH, RAYMOND |
发明人 |
HALLAHAN, DENNIS, E.;MERNAUGH, RAYMOND |
分类号 |
A61K41/00;A61K51/12;C07K16/28;C07K16/30;C12Q1/68;G01N33/68;(IPC1-7):C12Q1/68 |
主分类号 |
A61K41/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|