发明名称 |
CHIRAL 1,8-DIARYLNAPHTHALENES, METHODS OF MAKING THEM, AND THEIR USE AS SENSORS |
摘要 |
One aspect of the invention relates to 1,8-diarylnaphthalene compounds. In certain embodiments, a compound of the invention is an N-oxide of a 1,8-diarylnaphthalene. In certain embodiments, the aryl group is an optionally substituted acridyl group. In certain embodiments, a compound of the invention is a single steroisomer. In certain embodiments, a compound of the invention is a single enantiomer. Another aspect of the present invention relates to a method of detecting the presence of an analyte in a sample by monitoring the fluorescence of a compound of the invention in a sample. In certain embodiments, the analyte is a metal ion. Another aspect of the present invention relates to a method of determining the enantiomeric purity of an analyte by monitoring the fluorescence of a compound of the invention in the presence of the analyte. In certain embodiments, the analyte is a compound that is capable of hydrogen bonding. |
申请公布号 |
WO2005043124(A2) |
申请公布日期 |
2005.05.12 |
申请号 |
WO2004US36409 |
申请日期 |
2004.11.01 |
申请人 |
GEORGETOWN UNIVERSITY;WOLF, CHRISTIAN;MEI, XUEFENG |
发明人 |
WOLF, CHRISTIAN;MEI, XUEFENG |
分类号 |
A61K31/395;A61K31/44;A61K31/47;C07D213/02;C07D213/16;C07D213/89;C07D215/00;C07D217/00;C07D219/02;C07D221/18;C07D307/00;C07D401/02;G01N;G01N33/52 |
主分类号 |
A61K31/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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