The invention relates to the identification and selection of biomarkers which demonstrate particular advantage in identifying individuals having liver cancer. The invention further relates to useful combinations of biomarkers for diagnosing liver cancer. The invention further provides for the polynucleotides and polypeptides and kits thereof for use as a tool to diagnose disease and to monitor the efficacy of therapeutic regimens. The invention further provides a method of selecting biomarker combinations and the combinations thus identified for diagnosis of liver cancer. Also encompassed by the invention are screening methods to identify therapeutic targets for treating liver cancer, and identify single nucleotide point mutations related to liver cancer.
申请公布号
WO2005042725(A2)
申请公布日期
2005.05.12
申请号
WO2004US36603
申请日期
2004.11.03
申请人
GENENEWS, INC.;LIEW, CHOONG-CHIN;WILLIAMS, KATHLEEN, M.;YAGER, TOM;DEMPSEY, ADAM;CHAO, MANUEL
发明人
LIEW, CHOONG-CHIN;YAGER, TOM;DEMPSEY, ADAM;CHAO, MANUEL