Bicyclic derivative, its production and use

摘要

The present invention provides a heterocyclic compound having potent tyrosine kinase-inhibiting activity represented by formula: (wherein, R^1b is a C_6-10 aryl group which has substituent(s), and the like; T^a is a single bond, a C_1-6 alkyl group, -CH₂O-, and the like; X and Y are the same or different, and each is a nitrogen atom which may have substituent(s), and the like; the broken line is a single bond or a double bond; Z^a is a nitrogen atom or CH; W is a single bond, an oxygen atom, and the like; Q is a C_6-10 aryl group which may have substituent(s) or an aromatic heterocyclic group which may have substituent(s)); or a salt thereof and a pharmaceutical composition comprising thereof.