发明名称 |
ALPHA SUBSTITUTED CARBOXYLIC ACID AS PPAR MODULATORS |
摘要 |
Alpha substituted carboxylic acids of formula (I): wherein R' and R2 are as defined in the specification and R3 is A) formula (II); B) formula (III); C) formula (IV); and D) formula (V); wherein Y, Art, Are, AP, R4, R5, R6, R7, R6, R9, R9a, R10, R", R12, R17, ring A, and p are as defined in the specification; pharmaceutical compositions containing effective amounts of said compounds or their salts are useful for treating PPAR, specifically PPAR alpha/y related disorders, such as diabetes, dyslipidemia, obesity and inflammatory disorders.
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申请公布号 |
WO2004092145(A8) |
申请公布日期 |
2005.05.12 |
申请号 |
WO2004IB01159 |
申请日期 |
2004.04.01 |
申请人 |
PFIZER INC.;BAILEY, SIMON;HUMPHRIES, PAUL, STUART;SKALITZKY, DONALD, JAMES;SU, WEI-GUO;ZEHNDER, LUKE, RAYMOND |
发明人 |
BAILEY, SIMON;HUMPHRIES, PAUL, STUART;SKALITZKY, DONALD, JAMES;SU, WEI-GUO;ZEHNDER, LUKE, RAYMOND |
分类号 |
C07C59/125;C07C59/68;C07C61/04;C07C62/34;C07C249/06;C07C271/14;C07C271/16;C07C311/08;C07C311/29;C07C317/22;C07D213/66;C07D249/06;C07D263/32;C07D307/79;C07D401/04;C07D405/06;C07D413/12;C07D413/14;C07D417/14;(IPC1-7):C07D263/32;C07D411/12 |
主分类号 |
C07C59/125 |
代理机构 |
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代理人 |
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