Fluorescence spectroscopy is used to analyze small numbers of molecules that are present in a relatively small detection volume or zone. Information regarding physical and chemical properties of these molecules is determined by rapidly modulating the wavelength, intensity and/or polarization of laser energy to excite fluorophores that are attached either to the molecule of interest or a molecule that interacts with the molecule of interest. The emission profile of the fluorophores is used to determine useful information about the labeled and/or non-labeled molecules including molecular interactions between the molecules.
申请公布号
WO2005008212(A3)
申请公布日期
2005.05.12
申请号
WO2004US19709
申请日期
2004.06.17
申请人
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;WEISS, SHIMON;KAPANIDIS, ACHILLEFS;LAURENCE, TED, A.;LEE, NAM K.
发明人
WEISS, SHIMON;KAPANIDIS, ACHILLEFS;LAURENCE, TED, A.;LEE, NAM K.