发明名称 |
Card-domain containing polypeptides, encoding nucleic acids, and methods of use |
摘要 |
The invention provides caspase recruitment domain (CARD)-containing polypeptides and functional fragments thereof, encoding nucleic acid molecules, and specific antibodies. Also provided are screening methods for identifying CARD-associated polypeptides (CAPs), and for identifying agents that alter the association of a CARD-containing polypeptide with itself or with a CAP. Further provided are methods of altering a biochemical process modulated by a CARD-containing polypeptide, and methods of diagnosing a pathology characterized by an increased or decreased level of a CARD-containing polypeptide.
|
申请公布号 |
US2005100941(A1) |
申请公布日期 |
2005.05.12 |
申请号 |
US20040961569 |
申请日期 |
2004.10.08 |
申请人 |
THE BURNHAM INSTITUTE |
发明人 |
PAWLOWSKI KRZYSZTOF;REED JOHN C.;GODZIK ADAM |
分类号 |
A61K38/00;C07K14/47;(IPC1-7):C12Q1/68;G01N33/574;C07H21/04 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|