发明名称 |
Ligands, including antibodies, showing reactivity against endocrine cells |
摘要 |
The invention provides monoclonal and polyclonal antibodies recognising molecules on secretory cells of various tissue targets of autoimmune disease allowing a unifying method of preventing and treating autoimmune diseases and other conditions where hormonal dysregulation, hyperinsulinaemia and insulin resistance are involved. It also provides a method for detecting similar antibodies in human sera or other body fluids which can be used in the development of diagnostic kits. Treatment methods arising from this invention comprise the administration of preparations of the antibodies, their target molecules and vectors containing coding sequences of the antibodies and their target molecules.
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申请公布号 |
US2005100541(A1) |
申请公布日期 |
2005.05.12 |
申请号 |
US20030674433 |
申请日期 |
2003.10.01 |
申请人 |
MATOSSIAN-ROGERS ARPI |
发明人 |
MATOSSIAN-ROGERS ARPI |
分类号 |
C12N15/09;A61K38/00;A61K38/16;A61K38/17;A61K39/395;A61P3/10;A61P9/00;A61P35/00;A61P37/06;A61P43/00;C07K14/435;C07K14/47;C07K16/00;C07K16/42;C12P21/02;C12P21/08;G01N33/564;G01N33/68;(IPC1-7):A61K39/395 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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