摘要 |
A remedy and/or preventive for diseases due to myelopathy which comprises as the active ingredient a compound represented by the general formula (I): (wherein Y represents sulfonyl or carbonyl; R<SUP>1 </SUP>and R<SUP>2 </SUP>each represents hydrogen, alkyl, or -X-A-(R<SUP>4</SUP>)<SUB>n </SUB>or NR<SUP>1</SUP>R<SUP>2 </SUP>represents a heterocycle; R<SUP>3 </SUP>represents OH, alkyl, etc.; and m is an integer of 0 to 4), a non-toxic salt of the compound, or a hydrate of the compound. The compound represented by the general formula (I), non-toxic salt, and hydrate are useful for the treatment and/or prevention of diseases due to myelopathy, e.g., spinal cord injury, spinal cord ischemia-reprefusion injury, or central nervous system disorders accompanying these.
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