发明名称 |
Antigenic conjugates of conserved lipooligosaccharides of gram negative bacteria |
摘要 |
Antigenic conjugates are provided which comprise a carrier protein covalently bonded to the conserved portion of a lipopolysaccharide of a gram negative bacteria, wherein said conserved portion of the lipopolysaccharide comprises the inner core and lipid A portions of said lipopolysaccharide, said conjugate eliciting a cross reactive immune response against heterologous strains of said gram negative bacteria. |
申请公布号 |
EP0941738(B1) |
申请公布日期 |
2005.05.11 |
申请号 |
EP19990301747 |
申请日期 |
1999.03.09 |
申请人 |
WYETH HOLDINGS CORPORATION |
发明人 |
ARUMUGHAM, RASAPPA G.;FORTUNA-NEVIN, MARIA;APICELLA, MICHAEL A.;GIBSON, BRADFORD W. |
分类号 |
A61K39/02;A61K31/00;A61K39/08;A61K39/09;A61K39/095;A61K39/10;A61K39/104;A61K39/108;A61K39/112;A61K39/118;A61K39/385;A61P31/04;A61P37/00;A61P37/02;C07K14/34;(IPC1-7):A61K39/385 |
主分类号 |
A61K39/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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