| 发明名称 |
THERAPEUTIC USE OF KREMEN 1 AND 2, INHIBITORS OF THE CANONICAL WNT-SIGNAL TRANSDUCTION |
| 摘要 |
The present invention relates to a composition useful for the diagnosis of diseases associated with aberrant expression of the gene encoding the receptor Kremen 1 and/or Kremen 2 e.g. tumors or diseases of the kidneys, bones and eyes. The present invention also relates to a pharmaceutical composition containing a compound which is capable of modifying (a) the expression of the gene encoding Kremen 1 and/or Kremen 2 or (b) the activity of the Kremen 1 and/or Kremen 2 receptor. |
| 申请公布号 |
EP1529062(A2) |
申请公布日期 |
2005.05.11 |
| 申请号 |
EP20030746281 |
申请日期 |
2003.03.28 |
| 申请人 |
DEUTSCHES KREBSFORSCHUNGSZENTRUMSTIFTUNG DES OEFFENTLICHEN RECHTS |
发明人 |
NIEHRS, CHRISTOF;MAO, BINGYU |
| 分类号 |
A61K31/7088;A61K38/00;A61K38/17;A61K39/395;A61K45/00;A61K48/00;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P13/12;A61P19/00;A61P19/08;A61P27/02;A61P35/00;A61P43/00;C07K14/705;C07K16/28;C12N15/09;C12Q1/02;C12Q1/68;G01N33/15;G01N33/50;G01N33/53;G01N33/566;G01N33/574;G01N37/00;(IPC1-7):C07K14/705;A61K31/708 |
主分类号 |
A61K31/7088 |
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