发明名称 1-ОКСА-3-АЗАДИБЕНЗОАЗУЛЕНЫ В КАЧЕСТВЕ ИНГИБИТОРОВ ПРОДУЦИРОВАНИЯ ФАКТОРА НЕКРОЗА ОПУХОЛИ И ПРОМЕЖУТОЧНЫЕ ПРОДУКТЫ ДЛЯ ИХ ПОЛУЧЕНИЯ
摘要 The present invention relates to derivatives of 1-oxa-3-aza-dibenzoazulene class, to their pharmacologically acceptable salts and solvates, to processes and intermediates for the preparation thereof as well as to their antiinflammatory actions, especially to the inhibition of tumour necrosis factor-alpha (TNF-alpha) production and the inhibition of interleukin-1 (IL-1) production as well as to their analgetic action.
申请公布号 RU2004132867(A) 申请公布日期 2005.05.10
申请号 RU20040132867 申请日期 2003.04.09
申请人 ПЛИВА-ИСТРАЖИВАЧКИ ИНСТИТУТ Д.О.О. (HR) 发明人 МЕРЧЕП Младен (HR);МЕСИЧ Милан (HR);ПЕСИЧ Ди на (HR);БЕНКО Ива (HR)
分类号 C07D498/04;A61K31/42;A61K31/424;A61P1/04;A61P11/06;A61P17/04;A61P17/06;A61P17/16;A61P19/02;A61P19/08;A61P27/02;A61P29/00;A61P43/00;C07D263/52 主分类号 C07D498/04
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