НОВОЕ ПРИМЕНЕНИЕ ЗАМЕЩЕННЫХ АМИНОМЕТИЛХРОМАНОВ ДЛЯ ЛЕЧЕНИЯ НАРУШЕНИЙ ДВИЖЕНИЙ ИЛИ НЕЖЕЛАТЕЛЬНЫХ ДЕЙСТВИЙ, ВЫЗЫВАЕМЫХ СРЕДСТВАМИ, КОТОРЫЕ ВВОДЯТСЯ ДЛЯ ЛЕЧЕНИЯ ЭКСТРАПИРАМИДНЫХ НАРУШЕНИЙ ДВИЖЕНИЙ

摘要

Substituted aminomethyl chromans, one of their optical isomers or pharmaceutically acceptable salts, used for the manufacture of a medicament for the treatment of adverse effects of anti-Parkinsonian drugs in extrapyramidal movement disorders and/or for the manufacture of a medicament for the treatment of extrapyramidal symptoms (EPS) induced by neuroleptics. A preferred compound is (-)-(R)-2-{4-[[3,4-dihydro-2H-benzopyran-2-yl)-methyl!amino!butyl}-1,2-benzoisothiazol-3-(2H)-on-1,1-dioxide or a physiologically acceptable salt thereof.