发明名称 ПРОИЗВОДНЫЕ БЕНЗОТИАЗЕПИНА И БЕНЗОТИАДИАЗЕПИНА, КОТОРЫЕ ИНГИБИРУЮТ ПЕРЕНОС ЖЕЛЧНЫХ КИСЛОТ В ПОДВЗДОШНОЙ КИШКЕ (IBAT), ДЛЯ ЛЕЧЕНИЯ ГИПЕРЛИПЕМИИ
摘要 The present invention relates to compounds of formula (I) wherein R<SUP>v</SUP>, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>x</SUP>, R<SUP>y</SUP>, M, R<SUP>z</SUP>, v, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5 </SUP>and R<SUP>6 </SUP>are as defined within; pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Processes for their manufacture and pharmaceutical compositions containing them are also described.
申请公布号 RU2004110716(A) 申请公布日期 2005.05.10
申请号 RU20040110716 申请日期 2002.09.05
申请人 АСТРАЗЕНЕКА АБ (SE) 发明人 СТАРКЕ Ингемар (SE);ДАЛЬСТРУМ Микаэль Ульф Юхан (SE);БЛУМБЕРГ Давид (SE);АЛЕНФАЛЬК Сузанне (SE);ШАРЕТ Туре (SE);ЛЕМУРЕЛЛЬ Малин (SE)
分类号 A61K;A61K31/192;A61K31/397;A61K31/40;A61K31/505;A61K31/554;A61K31/695;A61K31/785;A61P;A61P3/06;A61P7/02;A61P9/00;A61P9/04;A61P9/06;A61P9/08;A61P9/10;A61P17/02;A61P31/00;A61P43/00;C07D;C07D281/02;C07D281/10;C07D285/36;C07D417/12;C07F7/10;C07K 主分类号 A61K
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