| 发明名称 |
VIRALLY-SAFE FACTOR VIII WITH A LOW CONTENT OF HIGHER MULTIMERS |
| 摘要 |
<p>La present invention pertains to a composition of plasma-derived virally-safe factor VIII, obtained after nanometric filtration, said composition comprising von Willebrand factor (vWF) at a rate of 15% or less of decamers and higher multimers. Such compositions have a reduction factor of the virus titre higher than 4 log and are thus suitable for treatment of hemophilia.</p> |
| 申请公布号 |
WO2005040214(A1) |
申请公布日期 |
2005.05.06 |
| 申请号 |
WO2004FR02737 |
申请日期 |
2004.10.25 |
| 申请人 |
LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES;CHTOUROU, ABDESSATAR;NOGRE, MICHEL;SCHMITTHAEUSLER, ROLAND |
发明人 |
CHTOUROU, ABDESSATAR;NOGRE, MICHEL;SCHMITTHAEUSLER, ROLAND |
| 分类号 |
A61K38/00;A61K38/37;A61L2/00;A61P7/04;C07K1/34;C07K14/755;C12Q1/04;C12Q1/56;G01N33/68;G01N33/86;(IPC1-7):C07K14/755 |
主分类号 |
A61K38/00 |
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