ACYL- PHOSPHATE AND PHOSPHONATE PROBES AND METHODS OF THEIR SYNTHESIS AND USE IN PROTEOMIC ANALYSIS
摘要
The present invention provides tagged acyl phosphate probes ("TAPPs"), and methods of their preparation and use. The subject methods and compositions can provide enhanced simplicity and accuracy in identifying changes in the presence, amount, or activity of target proteins in a complex protein mixture, preferably nucleotide binding proteins using nucleotide binding protein-directed TAPPs. The profiling methods described herein can have a number of steps leading to the identification of target nucleotide binding protein(s) in a complex protein mixture.
申请公布号
WO2004090154(A3)
申请公布日期
2005.05.06
申请号
WO2004US10075
申请日期
2004.04.01
申请人
ACTIVX BIOSCIENCES, INC.;CAMPBELL, DAVID, ALAN;LIYANAGE, MAREK;SZARDENINGS, ANNA, KATRIN;WU, MIN
发明人
CAMPBELL, DAVID, ALAN;LIYANAGE, MAREK;SZARDENINGS, ANNA, KATRIN;WU, MIN