发明名称 |
ADVANCED SYNCHRONOUS LUMINESCENSE IMAGING FOR CHEMICAL AND MEDICAL DIAGNOSTICS |
摘要 |
A diagnostic method and associated system includes the steps of exposing at least one sample location with excitation radiation through a single optical waveguide or a single optical waveguide bundle. wherein the sample emits emission radiation in response to the excitation radiation. The same single optical waveguide or the single optical waveguide bundle receives at least a portion of the emission radiation from the sample, thus providing co-registration of the excitation radiation and the emission radiation. The wavelength of the excitation radiation and emission radiation is synchronously scanned to produce a spectrum upon which an image can be formed. An increased emission signal is generated by the enhanced overlap of the excitation and emission local volumes provided by co-registration of the excitation and emission signals thus increasing the sensitivity as well as decreasing the exposure time necessary to obtain an image. |
申请公布号 |
WO2005039385(A2) |
申请公布日期 |
2005.05.06 |
申请号 |
WO2004US32372 |
申请日期 |
2004.10.01 |
申请人 |
UT-BATTELLE, LLC;VO-DINH, TUAN |
发明人 |
VO-DINH, TUAN |
分类号 |
A61B5/00;G01N21/64 |
主分类号 |
A61B5/00 |
代理机构 |
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